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In this era of biotechnology there have been many books covering the fundamentals of recombinant DNA technology and protein chemistry. However, not many sources are available for the pharmaceutical develop­ ment scientist and other personnel responsible for the commercialization of the finished dosage forms of these new biopharmaceuticals and other products from biotechnology. This text will help to fill this gap. Once active biopharmaceutical molecules are candidates for clinical trial investigation and subsequent commercialization, a number of other activities must take place while research and development on these molecules continues. The active ingredient itself must be formulated into a finished dosage form that can be conveniently used by health care professionals and patients. Properties of the biopharmaceutical molecule must be clearly understood so that the appropriate finished product formulation can be developed. Finished product formulation development includes not only the chemical formulation, but also the packaging system, the manufacturing process, and appropriate control strategies to assure such good manufacturing practice attributes as safety, identity, strength, purity, and quality.

• Sales Rank: #3147702 in Books
• Published on: 2002-06-30
• Original language: English
• Number of items: 1
• Dimensions: 9.02" h x 1.25" w x 5.98" l, 1.87 pounds
• Binding: Hardcover
• 464 pages

Most helpful customer reviews

2 of 2 people found the following review helpful.
diverse topics
By W Boudville
The book is a collection of research chapters on various aspects of protein pharmaceuticals, contributed by authors who are at firms in this industry. The topics are broad.

One topic is how to thermally sterilise the manufacturing. There's some elementary thermodynamics and kinetics covered here, that centres on killing off microbes. A key idea is that sterility is not an absolute, binary concept, but is modelled by a probability distribution. A pragmatic recognition that absolute assurance is often unnecessary and too expensive.

Typically, the chapters contain a mixture of basic chemistry and biology, along with engineering issues and diagrams that are needed in a production environment.

See all 1 customer reviews...

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• Sales Rank: #749889 in Books
• Published on: 2014-05-16
• Original language: English
• Number of items: 1
• Dimensions: 9.00" h x .50" w x 6.00" l, .65 pounds
• Binding: Paperback
• 198 pages

About the Author
ALAN COLLINS has interviewed and hired hundreds of Human Resources professionals at all levels in his 25 years of HR experience in Fortune 100 companies.  He was formerly Vice President of Human Resources at PepsiCo where he led HR initiatives for their Quaker Oats, Gatorade and Tropicana businesses.  Today, he is founder of Success in HR where he currently serves 12,000+ HR subscribers around the globe through his flagship newsletter, "Success in HR" and countless others through his books, presentations and coaching. He has written over 100 articles and white papers on human resources topics and earned his BS in Management and MS in Human Resources from Purdue University.  His works can be accessed at: SuccessInHR.com. 

Most helpful customer reviews

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helpful insights

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By Jon Rupert
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See all 20 customer reviews...

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This engaging text takes an evenhanded approach to major theoretical paradigms in evaluation and builds a bridge from them to evaluation practice. Featuring helpful checklists, procedural steps, provocative questions that invite readers to explore their own theoretical assumptions, and practical exercises, the book provides concrete guidance for conducting large- and small-scale evaluations. Numerous sample studies—many with reflective commentary from the evaluators—reveal the process through which an evaluator incorporates a paradigm into an actual research project. The book shows how theory informs methodological choices (the specifics of planning, implementing, and using evaluations). It offers balanced coverage of quantitative, qualitative, and mixed methods approaches.   Useful pedagogical features include: *Examples of large- and small-scale evaluations from multiple disciplines. *Beginning-of-chapter reflection questions that set the stage for the material covered. *"Extending your thinking" questions and practical activities that help readers apply particular theoretical paradigms in their own evaluation projects. *Relevant Web links, including pathways to more details about sampling, data collection, and analysis. *Boxes offering a closer look at key evaluation concepts and additional studies. *Checklists for readers to determine if they have followed recommended practice.  

 

• Sales Rank: #3416169 in Books
• Published on: 2012-02-20
• Original language: English
• Number of items: 1
• Dimensions: 10.00" h x 1.30" w x 7.20" l, 2.70 pounds
• Binding: Hardcover
• 621 pages

Review
"Written in clear, jargon-free prose, this is a coherent and pragmatic guide for students and practitioners in any discipline who are involved in evaluation theory and practice. Doing justice to the various branches and theories informing evaluation practice, the text presents real-world evaluation examples and lessons with an acute understanding of the limitations and politics that evaluators must navigate. Its strong pedagogical apparatus encompasses graphic organizers, application exercises, Web resources, and self-reflection questions, all grounded in concrete examples and applications from across fields and disciplines. Mertens and Wilson’s book is a boon for graduate students and teachers."--Sharona A. Levy, DPhil, Chair and Director, SEEK (Search for Education, Elevation, and Knowledge) Program, Brooklyn College, City University of New York

"I was pleased to see the broad scope of this book, which sets it apart from many others that focus on a single aspect of evaluation. The authors put evaluation in its proper historical context before moving on to methodology and the planning and implementation phases of this unique type of research. The book stimulates critical thinking while helping readers become more savvy producers and consumers of research."--Wendy L. Hicks, PhD, Department of Criminal Justice, Loyola University New Orleans

"This text provides a comprehensive, thorough presentation of program evaluation as an enterprise with a rich history, diverse perspectives, and widely varied applications. Among the best features of this text is the consistent use of well-conceived questions to transition readers' thinking between chapters and constantly challenge them to consider multiple perspectives. The text strikes a good balance between epistemological and theoretical understanding and practical applications."--Steven R. Rogg, PhD, Lesson Study Alliance, Chicago, Illinois

"Standing out in a sea of evaluation texts, this book takes evaluation training to another level. It provides a solid, coherent discussion of the field in the 21st century. Mertens and Wilson address step-by-step methodological considerations in conducting evaluations, with special attention to the transformative paradigm. Illustrating how mixed method evaluations are conducted in a variety of settings, the book goes beyond buzzwords to demonstrate concrete strategies that are used in the field. What really sets this book apart is the opportunity it affords students and practicing evaluators to think through their evaluation practices more deeply, considering not only the methods they use but also the general philosophy that drives every evaluation they conduct. A 'must have' for students, scholars, and practitioners."--Katrina L. Bledsoe, PhD, Education Development Center, Inc., Washington, DC

"A refreshing feature of this text is its coverage of philosophical perspectives and their relationship to evaluation approaches. The book makes an important contribution in helping readers understand their own views of evaluation and how paradigms shape the evolution of evaluation theory. The organization of evaluation paradigms into four branches--the methods, use, values, and social justice branches--offers a useful analytic lens that accurately represents current directions in the field."--Linda B. Schrader, Department of Educational Leadership and Policy Studies, Florida State University

"Mertens and Wilson want students to think about and actively decide what theoretical and philosophical position they will take in their evaluation practice: post-positivist, constructivist, pragmatic, or transformative. Evaluation examples combined with provocative questioning will challenge what students think they know and how they know it. Preparation for undertaking an evaluation does not stop here--Mertens and Wilson continue to raise issues of politics, power, and privilege as they take students through planning and implementing an evaluation. As expected, Mertens and Wilson have provided an exposition of evaluation that has both style and worth."--Fiona Cram, PhD, Director, Katoa Ltd, New Zealand

About the Author
Donna M. Mertens is Professor in the Department of Educational Foundations and Research at Gallaudet University, where she teaches advanced research methods and program evaluation to deaf and hearing students. She received the Distinguished Faculty Award from Gallaudet. The primary focus of her work is transformative mixed methods inquiry in diverse communities, with priority given to the ethical implications of research in pursuit of social justice. A past president of the American Evaluation Association (AEA), Dr. Mertens provided leadership in the development of the International Organization for Cooperation in Evaluation and the establishment of the AEA Diversity Internship Program with Duquesne University. She has received AEA’s highest honors for service to the organization and the field, as well as for her contributions to evaluation theory. She is the author of several books and is widely published in major professional journals. Dr. Mertens conducts and consults on evaluations in many countries, including Egypt, India, South Africa, Botswana, Israel, Australia, New Zealand, and Costa Rica. Amy T. Wilson is Director of International Programs at the Mill Neck Family of Organizations, where she leads a team of deaf educational specialists who share their expertise, knowledge, and technical skills with parents, educators, and professionals in economically poor countries. Dr. Wilson was a professor in the Department of Educational Foundations and Research at Gallaudet University for 14 years. After living in developing countries and noting the poor assistance people with disabilities were receiving from U.S. development organizations, she developed Gallaudet’s MA degree in International Development. The degree, which is the only one of its kind in the United States, focuses on the inclusion of people with disabilities in development assistance programs and in nongovernmental, federal, and faith-based development organizations both in the United States and overseas. Dr. Wilson was Program Director of the International Development Program; she also taught deaf and hearing students research and evaluation, theory and practice of international development, micropolitics, community development with people with disabilities, multicultural education, and gender, disability, and development. Dr. Wilson evaluates and advises development organizations and agencies (e.g., U.S. Agency for International Development, the InterAmerican Development Bank, the World Bank, and the Peace Corps) about the inclusiveness of their programs, as well as their effectiveness with various disability communities.

Most helpful customer reviews

0 of 0 people found the following review helpful.
A decent introduction to program evaluation
By C. Ramirez
A student's guide to program evaluation that relief equally on theory as it does on practice. I was hoping for something more practical though.

0 of 0 people found the following review helpful.
Stimulant.
By Edilson Correia Alves Lima
General vision of de field with an excelent and pragmatic approach for students and professionals. This work provides a stimulant reading and a willingness to put our learnign in practice.

0 of 0 people found the following review helpful.
Good
By Daniel Gonzales
Good, helpful for my college course and it was recommended by my professor to buy this book and got it on Amazon.com

See all 11 customer reviews...

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Annabelle Forest was just seven years old when she was inducted into a twisted sex cult by her own mother. For the next few years she was brainwashed by the cult's leader, Colin Batley, who ran a harem of followers from his unassuming cul-de-sac in Kidwelly, Wales. Batley ruled the cult with an iron will, his twisted ideology based on Aleister Crowley's Book of the Law, which informed their day-to-day lives. From the age of 11, Annabelle was repeatedly raped by Batley, and threatened with going to hell if she angered 'the gods' by refusing Batley's sick demands. Annabelle's mother joined in the sessions and even filmed them. Annabelle lived a double life - a schoolgirl by day, a sex slave at night. It might have endured for years had she not fallen pregnant at 17 with Batley's baby. In February 2008 she gave birth to a daughter, Emily, who gave Annabelle hope and a reason to live. Now she knew she had to escape, especially after Batley forced her into prostitution when Emily was three months old. She contacted relatives and found the courage to report Batley, her mother and the other cult members to the police. In 2011 her evidence helped convict 48-year-old Batley for life on 11 charges of rape and numerous other sexual offences.Annabelle's mother was also jailed, along with two others in a case that came to be known as the 'cul-de-sac cult'. Today she lives a happy and settled life with Emily and her partner but the nightmares of her damaged past will haunt her forever.

• Sales Rank: #790497 in Books
• Published on: 2014-08-14
• Original language: English
• Dimensions: 7.80" h x .79" w x 5.12" l, .60 pounds
• Binding: Paperback
• 272 pages

About the Author
Annabelle Forest is the pseudonym of the young woman who helped convict cult leader Colin Batley, who had raped and abused her. For legal reasons her true identity cannot be revealed Katy Weitz in an experienced writer of inspirational memoir.

Most helpful customer reviews

0 of 0 people found the following review helpful.
Astonished and captivating
By TRACI-LU
The minute I tuned into "Nightmare in suburbia - The cul de sac sex cult" - I immediately turned the telly off and download the Amazon book. This shockingly true story had me captivated and horrified from beginning to end and I could not put this book down. With tears streaming down my face my admiration for this young lady ensuring that justice was served, over and above her trauma, has left me happy and angry - an excellent read!

7 of 7 people found the following review helpful.
A Most Remarkable Story
By PMS
This book will bring tears to your eyes for it is one of the most shocking accounts of child abuse ever told by a victim.

Well done to the victim for sharing this real life nightmare that she endured for too many years. Her story is a very disturbing one indeed. It makes one wonder to what extent it could be happening in other places, to other innocent girls.

Her story is about her 'hell on earth childhood' and how she was intentionally manipulated, brainwashed, abused and psychologically tortured from a very young age, growing up within a secret religious sex cult.

Despite her ordeal, however, she managed to find the strength to overcome her evil predicament, survive the trauma and pain, and help see justice done.

Despite all she endured, what is truly inspiring is how she was able to put it all behind her and become a normal caring loving person who finally found happiness and a positive attitude to life.

A must read book!

4 of 4 people found the following review helpful.
An Unreal Reading experience
By Iris de Vree
Written in the perfect style for this kind of story. It takes you away to the memories of Annabelle Foster. Its unbelievable she went through so much and still found the strength and courage to keep going and start a new life. I admire her and I hope she bringing hope to people who have been or are in a similar situation.

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Sit in with the band and bring your playing to life!

Soloing is an important part of your playing, but practicing on your own doesn't always get the creative juices flowing because there is nothing quite like the experience of sitting in with a full band. Since jamming with other musicians is not always possible, Sitting In: Jazz Guitar brings the band to you! Practice comping and soloing with the same energy you get with a real, live band. Expert guitarist Jody Fisher leads you through all the tips and ideas you need to give life to your practice sessions, inspiring you to add new sounds to your growing jazz vocabulary.

The DVD-ROM includes MP3 audio for every song in full-band mixes for demonstration and rhythm section-only mixes so that you can stretch out. The included TNT 2 software is the perfect practice tool, allowing you customize audio tracks for practice. Use it to slow down tracks, isolate and loop parts, and change tempos and keys.

• Sales Rank: #1079026 in Books
• Brand: Alfred
• Model: 00-44436
• Published on: 2015-10-01
• Original language: English
• Number of items: 1
• Dimensions: 11.80" h x .30" w x 9.20" l, .60 pounds
• Binding: Paperback
• 80 pages

Most helpful customer reviews

3 of 3 people found the following review helpful.
Awesome. I only started by reading the first ten ...
By Amazon Customer
Awesome. I only started by reading the first ten pages or so, but I can already tell that this is the book I've been looking for for a long time. I owned Jody's Alfred beginning jazz book/DVDs awhile back and really liked it: Jody is good at taking jazz concepts and really breaking them down to their foundations, to easier understand them. I am really looking forward to getting into this book, because I can tell that it will help me improve at jazz soloing if I spend the time and effort.

4 of 5 people found the following review helpful.
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By Bill the Cat
I own practically every book Jody has written, and I love them all. If there's anything Jody Fisher doesn't know about the guitar, it isn't worth knowing. I buy his books as soon as I see his name on them. How's that for a good review?

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